IDH1-R132H mutation radiosensitizes U87MG glioma cells via epigenetic downregulation of TIGAR

Yin, NR; Xie, T; Zhang, HW; Chen, J; Yu, JH; Liu, FJ

Liu, FJ (corresponding author), Soochow Univ, Sch Radiat Med & Protect, State Key Lab Radiat Med & Protect, Med Coll, 199 Ren Ai Rd, Suzhou 215123, Jiangsu, Peoples R China.

ONCOLOGY LETTERS, 2020; 19 (2): 1322

Abstract

Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated gene in World Health Organization grade II-III and secondary glioma. The majority of ......

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