Repurposing BCL-2 and Jak 1/2 inhibitors: Cure and treatment of HIV-1 and other viral infections

Reece, MD; Song, CL; Hancock, SC; Ribeiro, SP; Kulpa, DA; Gavegnano, C

Gavegnano, C (通讯作者)，Emory Univ, Sch Med, Dept Pathol & Lab Med, Atlanta, GA 30322 USA.;Gavegnano, C (通讯作者)，Emory Univ, Sch Med, Dept Pharmacol & Chem Biol, Atlanta, GA 30322 USA.;Gavegnano, C (通讯作者)，Emory Univ, Coll Arts & Sci, Ctr Study Human Hlth, Atlanta, GA 30322 USA.;Gavegnano, C (通讯作者)，Atlanta Vet Affairs Med Ctr, Dept Pathol & Lab Med, Decatur, GA 30033 USA.;Gavegnano, C (通讯作者)，Harvard Med Sch, Ctr Bioeth, Boston, MA 02115 USA.

FRONTIERS IN IMMUNOLOGY, 2022; 13 ():

Abstract

B cell lymphoma 2 (BCL-2) family proteins are involved in the mitochondrial apoptotic pathway and are key modulators of cellular lifespan, which is dy......

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