Anti-C1 domain antibodies that accelerate factorVIII clearance contribute to antibody pathogenicity in a murine hemophiliaA model

Batsuli, G; Ito, J; Mercer, R; Baldwin, WH; Cox, C; Parker, ET; Healey, JF; Lollar, P; Meeks, SL

Meeks, SL (reprint author), Emory Childrens Ctr, 2015 Uppergate Dr,Room 442, Atlanta, GA 30322 USA.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2018; 16 (9): 1779

Abstract

Background The development of neutralizing anti-factorVIII (FVIII) antibodies remains a challenging complication of modern hemophiliaA care. Invitro a......

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