Cabozantinib Reverses Topotecan Resistance in Human Non-Small Cell Lung Cancer NCI-H460/TPT10 Cell Line and Tumor Xenograft Model

Lei, ZN; Teng, QX; Gupta, P; Zhang, W; Narayanan, S; Yang, DH; Wurpel, JND; Fan, YF; Chen, ZS

Chen, ZS (corresponding author), St Johns Univ, Coll Pharm & Hlth Sci, Dept Pharmaceut Sci, Queens, NY 11439 USA.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021; 9 ():

Abstract

Cabozantinib (CBZ) is a small molecule tyrosine kinase receptor inhibitor, which could also inhibit the ABCG2 transporter function. Therefore, CBZ cou......

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