Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi (R) and Epclusa (R)

Link, JO; Taylor, JG; Trejo-Martin, A; Kato, D; Katana, AA; Krygowski, ES; Yang, ZY; Zipfel, S; Cottell, JJ; Bacon, EM; Tran, CV; Yang, CY; Wang, YJ; Wang, KW; Zhao, GY; Cheng, GF; Tian, Y; Gong, RY; Lee, YJ; Yu, M; Gorman, E; Mogalian, E; Perry, JK

Link, JO (reprint author), Gilead Sci, Med Chem, 333 Lakeside Dr, Foster City, CA 94404 USA.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019; 29 (16): 2415

Abstract

Direct-acting antiviral inhibitors have revolutionized the treatment of hepatitis C virus (HCV) infected patients. Herein is described the discovery o......

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