Pharmacologic Ascorbate and DNMT Inhibitors Increase DUOX Expression and Peroxide-Mediated Toxicity in Pancreatic Cancer

Steers, GJ; OLeary, BR; Du, J; Wagner, BA; Carroll, RS; Domann, FE; Goswami, PC; Buettner, GR; Cullen, JJ

Cullen, JJ (通讯作者)，Dept Radiat Oncol, Free Rad & Radiat Biol Div, Iowa City, IA 52242 USA.;Cullen, JJ (通讯作者)，Univ Iowa, Carver Coll Med, Dept Surg, Iowa City, IA 52242 USA.

ANTIOXIDANTS, 2023; 12 (9):

Abstract

Recent studies have demonstrated an important role for vitamin C in the epigenetic regulation of cancer-related genes via DNA demethylation by the ten......

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