PKA-RII beta autophosphorylation modulates PKA activity and seizure phenotypes in mice

Zhang, JL; Zhang, CY; Chen, XL; Wang, BW; Ma, WN; Yang, Y; Zheng, RM; Huang, Z

Huang, Z (corresponding author), Peking Univ, Sch Pharmaceut Sci, Dept Mol & Cellular Pharmacol, State Key Lab Nat & Biomimet Drugs,Hlth Sci Ctr, Beijing, Peoples R China.; Zheng, RM (corresponding author), Peking Univ, Sch Basic Med Sci, Hlth Sci Ctr, Dept Anat Histol & Embryol, Beijing, Peoples R China.; Zheng, RM (corresponding author), Peking Univ, Neurosci Res Inst, Beijing, Peoples R China.; Zheng, RM; Huang, Z (corresponding author), Minist Educ, Key Lab Neurosci, Beijing, Peoples R China

COMMUNICATIONS BIOLOGY, 2021; 4 (1):

Abstract

Temporal lobe epilepsy (TLE) is one of the most common and intractable neurological disorders in adults. Dysfunctional PKA signaling is causally linke......

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