Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1

Mill, CP; Fiskus, W; Das, K; Davis, JA; Birdwell, CE; Kadia, TM; DiNardo, CD; Daver, N; Takahashi, K; Sasaki, K; McGeehan, GM; Ruan, XJ; Su, XP; Loghavi, S; Kantarjian, H; Bhalla, KN

Bhalla, KN (通讯作者)，Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA.

LEUKEMIA, 2023; 37 (6): 1336

Abstract

In AML with NPM1 mutation causing cytoplasmic dislocation of NPM1, treatments with Menin inhibitor (MI) and standard AML chemotherapy yield complete r......

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