Vaginal microbiota and mucosal pharmacokinetics of tenofovir in healthy women using tenofovir and tenofovir/levonorgestrel vaginal rings

Thurman, AR; Schwartz, JL; Ravel, J; Gajer, P; Marzinke, MA; Yousefieh, N; Anderson, SM; Doncel, GF

Thurman, AR (reprint author), Eastern Virginia Med Sch, CONRAD, Norfolk, VA 23501 USA.

PLOS ONE, 2019; 14 (5):

Abstract

Recent data support that the vaginal microbiota may alter mucosal pharmacokinetics (PK) of topically delivered microbicides. Our team developed an int......

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