Siah2 control of T-regulatory cells limits anti-tumor immunity

Scortegagna, M; Hockemeyer, K; Dolgalev, I; Pozniak, J; Rambow, F; Li, Y; Feng, YM; Tinoco, R; Otero, DC; Zhang, TW; Brown, K; Bosenberg, M; Bradley, LM; Marine, JC; Aifantis, I; Ronai, ZA

Scortegagna, M; Ronai, ZA (corresponding author), Sanford Burnham Prebys Med Discovery Inst, Ctr Canc, La Jolla, CA 92037 USA.; Aifantis, I (corresponding author), NYU, Sch Med, Dept Pathol, New York, NY 10016 USA.; Aifantis, I (corresponding author), NYU, Sch Med, Isaac Perlmutter Canc Ctr, New York, NY 10016 USA.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Understanding the mechanisms underlying anti-tumor immunity is pivotal for improving immune-based cancer therapies. Here, we report that growth of BRA......

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