The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output

Kanellis, DC; Espinoza, JA; Zisi, A; Sakkas, E; Bartkova, J; Katsori, AM; Bostrom, J; Dyrskjot, L; Broholm, H; Altun, M; Elsasser, SJ; Lindstrom, MS; Bartek, J

Lindstrom, MS; Bartek, J (corresponding author), Karolinska Inst, Dept Med Biochem & Biophys, Div Genome Biol, Sci Life Lab, S-17121 Stockholm, Sweden.; Bartek, J (corresponding author), Danish Canc Soc, Res Ctr, DK-2100 Copenhagen, Denmark.

SCIENCE ADVANCES, 2021; 7 (32):

Abstract

Eukaryotic initiation factor 4A-III (eIF4A3), a core helicase component of the exon junction complex, is essential for splicing, mRNA trafficking, and......

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