Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies

Frame, AK; Robinson, JW; Mahmoudzadeh, NH; Tennessen, JM; Simon, AF; Cumming, RC

Frame, AK; Cumming, RC (通讯作者),Western Univ, Dept Biol, London, ON, Canada.

AGING-US, 2023; 15 (4):

Abstract

The astrocyte-neuron lactate shuttle hypothesis posits that glial-generated lactate is transported to neurons to fuel metabolic processes required for......

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