Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo

Czechowicz, JS; Nagel, CH; Voges, M; Spohn, M; Eibl, MM; Hauber, J

Hauber, J (reprint author), Heinrich Pette Inst, Leibniz Inst Expt Virol, Hamburg, Germany.; Hauber, J (reprint author), German Ctr Infect Res DZIF, Partner Site Hamburg, Hamburg, Germany.

PLOS ONE, 2018; 13 (8):

Abstract

Herpes Simplex Virus type 2 (HSV-2) is a neurotropic human pathogen. Upon de novo infection, the viral infected cell protein 0 (ICP0) is immediately e......

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