SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

Klopfenstein, N; Brandt, SL; Castellanos, S; Gunzer, M; Blackman, A; Serezani, CH

Serezani, CH (corresponding author), Vanderbilt Univ, Dept Med, Div Infect Dis, Med Ctr, Nashville, TN 37235 USA.; Serezani, CH (corresponding author), Vanderbilt Univ, Dept Pathol Microbiol & Immunol, Nashville, TN 37235 USA.; Serezani, CH (corresponding author), Vanderbilt Univ, Vanderbilt Ctr Immunobiol, Med Ctr, Nashville, TN 37235 USA.; Serezani, CH (corresponding author), Vanderbilt Univ, Vanderbilt Inst Infect Immunol & Inflammat, Med Ctr, Nashville, TN 37235 USA.

PLOS PATHOGENS, 2021; 17 (3):

Abstract

Author summary The control of Staphylococcus aureus skin and soft tissue infections is dictated by the balance between pro- and anti-inflammatory acti......

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