RNAi mechanisms in Huntington's disease therapy: siRNA versus shRNA

Aguiar, S; van der Gaag, B; Cortese, FAB

Aguiar, S (reprint author), Univ Amsterdam, Swammerdam Inst Life Sci SILS CNS, Mol Neurosci Lab, Amsterdam, Netherlands.; Aguiar, S (reprint author), US Dept State IIE, Fulbright Program, New York, NY USA.

TRANSLATIONAL NEURODEGENERATION, 2017; 6 ( ):

Abstract

Huntington's Disease (HD) is a genetically dominant trinucleotide repeat disorder resulting from CAG repeats within the Huntingtin (HTT) gene exceedin......

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