High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma

Liu, JR; Yu, CW; Hung, PY; Hsin, LW; Chern, JW

Chern, JW (reprint author), Natl Taiwan Univ, Coll Med, Sch Pharm, 33 LinSen South Rd, Taipei 100, Taiwan.

BIOCHEMICAL PHARMACOLOGY, 2019; 163 (): 458

Abstract

Glioblastoma is the most fatal type of primary brain cancer, and current treatments for glioblastoma are insufficient. HDAC6 is overexpressed in gliob......

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