Transplantation of Skeletal Muscle-Derived Sca-1(+)/PW1(+)/Pax7(-) Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction

Ruchaya, PJ; Lewis-McDougall, FC; Sornkarn, N; Amin, S; Grimsdell, B; Shaalan, A; Gritti, G; Soe, KT; Clark, JE; Ellison-Hughes, GM

Ruchaya, PJ; Ellison-Hughes, GM (通讯作者)，Kings Coll London, Fac Life Sci & Med, Ctr Human & Appl Physiol Sci, Sch Basic & Med Biosci, London SE1 1UL, England.;Ruchaya, PJ; Ellison-Hughes, GM (通讯作者)，Kings Coll London, Fac Life Sci & Med, Ctr Gene Therapy & Regenerat Med, Sch Basic & Med Biosci, London SE1 1UL, England.;Ruchaya, PJ (通讯作者)，Univ East London, Sch Hlth,Sport & Biosci, Stratford Campus, London E16 2RD, England.

CELLS, 2022; 11 (24):

Abstract

We have previously shown that skeletal muscle-derived Sca-1(+)/PW1(+)/Pax7(-) interstitial cells (PICs) are multi-potent and enhance endogenous repair......

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