TRIM28 haploinsufficiency predisposes to Wilms tumor

Diets, IJ; Hoyer, J; Ekici, AB; Popp, B; Hoogerbrugge, N; van Reijmersdal, SV; Bhaskaran, R; Hadjihannas, M; Vasileiou, G; Thiel, CT; Seven, D; Uebe, S; Ilencikova, D; Waanders, E; Mavinkurve-Groothuis, AMC; Roeleveld, N; de Krijger, RR; Wegert, J; G

Metzler, M (reprint author), Friedrich Alexander Univ Erlangen Nurnberg FAU, Dept Pediat & Adolescent Med, Erlangen, Germany.

INTERNATIONAL JOURNAL OF CANCER, 2019; 145 (4): 941

Abstract

Two percent of patients with Wilms tumors have a positive family history. In many of these cases the genetic cause remains unresolved. By applying ger......

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