Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia

Fernandez, A; Gomez, MT; Vidal, R

Vidal, R (通讯作者),Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA.;Vidal, R (通讯作者),Indiana Univ Sch Med, Stark Neurosci Res Inst, Indianapolis, IN 46202 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2023; 299 (1):

Abstract

The Apolipoprotein E-e4 allele (APOE-e4) is the strongest genetic risk factor for late onset Alzheimer disease (AD). ApoE plays a critical role in amy......

Full Text Link