Optimal allosteric stabilization sites using contact stabilization analysis

Dickson, A; Bailey, CT; Karanicolas, J

Dickson, A (reprint author), Michigan State Univ, Dept Biochem & Mol Biol, E Lansing, MI 48824 USA.; Dickson, A (reprint author), Michigan State Univ, Dept Computat Math Sci & Engn, E Lansing, MI 48824 USA.

JOURNAL OF COMPUTATIONAL CHEMISTRY, 2017; 38 (15): 1138

Abstract

Proteins can be destabilized by a number of environmental factors such as temperature, pH, and mutation. The ability to subsequently restore function ......

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