PARP-DNA trapping ability of PARP inhibitors jeopardizes astrocyte viability: Implications for CNS disease therapeutics

Sinha, A; Katyal, S; Kauppinen, TM

Kauppinen, TM (corresponding author), Kleysen Inst Adv Med, SR434,710 William Ave, Winnipeg, MB R3E 0Z3, Canada.

NEUROPHARMACOLOGY, 2021; 187 ():

Abstract

There is emerging interest in the role of poly(ADP-ribose) polymerase-1 (PARP-1) in neurodegeneration and potential of its therapeutic targeting in ne......

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