IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis

Gross, AC; Cam, H; Phelps, DA; Saraf, AJ; Bid, HK; Cam, M; London, CA; Winget, SA; Arnold, MA; Brandolini, L; Mo, XK; Hinckley, JM; Houghton, PJ; Roberts, RD

Roberts, RD (reprint author), Room WA5021,700 Childrens Dr, Columbus, OH 43205 USA.

JCI INSIGHT, 2018; 3 (16):

Abstract

Osteosarcoma (OS), a malignant tumor of bone, kills through aggressive metastatic spread almost exclusively to the lung. Mechanisms driving this tropi......

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