Mortality Benefit of Recombinant Human Interleukin-1 Receptor Antagonist for Sepsis Varies by Initial Interleukin-1 Receptor Antagonist Plasma Concentration

Meyer, NJ; Reilly, JP; Anderson, BJ; Palakshappa, JA; Jones, TK; Dunn, TG; Shashaty, MGS; Feng, R; Christie, JD; Opal, SM

Meyer, NJ (reprint author), Univ Penn, Perelman Sch Med, Dept Med, Div Pulm Allergy & Crit Care Med, Philadelphia, PA 19104 USA.

CRITICAL CARE MEDICINE, 2018; 46 (1): 21

Abstract

Objective: Plasma interleukin-1 beta may influence sepsis mortality, yet recombinant human interleukin-1 receptor antagonist did not reduce mortality ......

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