The Flavagline Compound 1-(2-(dimethylamino) acetyl)-Rocaglaol Induces Apoptosis in K562 Cells by Regulating the PI3K/Akt/mTOR, JAK2/STAT3, and MAPK Pathways

Yang, XM; Wu, XJ; Wu, XS; Huang, L; Song, JR; Yuan, CM; He, ZX; Li, YM

Li, YM (通讯作者),Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Peoples R China.;He, ZX (通讯作者),Guizhou Med Univ, Stem Cell & Tissue Engn Res Ctr, Guiyang 550004, Peoples R China.

DRUG DESIGN DEVELOPMENT AND THERAPY, 2022; 16 (): 2545

Abstract

Purpose: Chronic myelogenous leukemia (CML) is a hematological malignancy with increased proliferation of cells of the myeloid series. This can disrup......

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