Aberrant Phosphorylation of SMAD4 Thr277-Mediated USP9x-SMAD4 Interaction by Free Fatty Acids Promotes Breast Cancer Metastasis

Wu, Y; Yu, XT; Yi, XH; Wu, K; Dwabe, S; Atefi, M; Elshimali, Y; Kemp, KT,; Bhat, K; Haro, J; Sarkissyan, M; Vadgama, JV

Wu, Y (reprint author), Charles R Drew Univ Med & Sci, 1748 E 118th St, Los Angeles, CA 90059 USA.

CANCER RESEARCH, 2017; 77 (6): 1383

Abstract

Obesity increases the risk of distant metastatic recurrence and reduces breast cancer survival. However, the mechanisms behind this pathology and iden......

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