ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms

Couts, KL; Bemis, J; Turner, JA; Bagby, SM; Murphy, D; Christiansen, J; Hintzsche, JD; Le, A; Pitts, TM; Wells, K; Applegate, A; Amato, C; Multani, P; Chow-Maneval, E; Tentler, JJ; Shellman, YG; Rioth, MJ; Tan, AC; Gonzalez, R; Medina, T; Doebele, RC

Couts, KL (reprint author), Univ Colorado, Anschutz Med Campus,12801 E 17th Ave,MS 8117, Aurora, CO 80045 USA.

MOLECULAR CANCER THERAPEUTICS, 2018; 17 (1): 222

Abstract

Oncogenic ALK fusions occur in several types of cancer and can be effectively treated with ALK inhibitors; however, ALK fusions and treatment response......

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