Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

Kang, SS; Ebbert, MTW; Baker, KE; Cook, C; Wang, XW; Sens, JP; Kocher, JP; Petrucelli, L; Fryer, JD

Kang, SS; Fryer, JD (reprint author), Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.; Fryer, JD (reprint author), Mayo Clin, Grad Sch Biomed Sci, Neurobiol Dis Grad Program, Jacksonville, FL 32224 USA.

JOURNAL OF EXPERIMENTAL MEDICINE, 2018; 215 (9): 2235

Abstract

Alzheimer's disease (AD) is an age-associated neurodegenerative disease characterized by amyloidosis, tauopathy, and activation of microglia, the brai......

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