Cutting Edge: IL-1 alpha and Not IL-1 beta Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality

Benjamin, JT; Moore, DJ; Bennett, C; van der Meer, R; Royce, A; Loveland, R; Wynn, JL

Wynn, JL (reprint author), Univ Florida, Coll Med, Dept Pediat, 1600 SW Archer Rd,POB 100296, Gainesville, FL 32610 USA.

JOURNAL OF IMMUNOLOGY, 2018; 201 (10): 2873

Abstract

Sepsis disproportionately affects the very old and the very young. IL-1 signaling is important in innate host defense but may also play a deleterious ......

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