CHK2-mediated regulation of PARP1 in oxidative DNA damage response

Hsu, PC; Gopinath, RK; Hsueh, YA; Shieh, SY

Shieh, SY (reprint author), Natl Def Med Ctr, Grad Inst Life Sci, Taipei 114, Taiwan.; Shieh, SY (reprint author), Acad Sinica, Inst Biomed Sci, 128 Sec 2,Acad Rd, Taipei 115, Taiwan.

ONCOGENE, 2019; 38 (8): 1166

Abstract

Poly(ADP-ribose) polymerase 1 (PARP1) is a DNA damage sensor, which upon activation, recruits downstream proteins by poly(ADP-ribosyl)ation (PARylatio......

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