BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis

Yalcinkaya, M; Liu, WL; Thomas, LA; Olszewska, M; Xiao, T; Abramowicz, S; Papapetrou, EP; Westerterp, M; Wang, N; Tabas, I; Tall, AR

Yalcinkaya, M; Tall, AR (通讯作者),Columbia Univ, Div Mol Med, Med Ctr, New York, NY 10032 USA.

CIRCULATION, 2023; 148 (22): 1764

Abstract

Background: Clonal hematopoiesis (CH) has emerged as an independent risk factor for atherosclerotic cardiovascular disease, with activation of macroph......

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