Highly Potent, Anthracycline-based Antibody-Drug Conjugates Generated by Enzymatic, Site-specific Conjugation

Stefan, N; Gebleux, R; Waldmeier, L; Hell, T; Escher, M; Wolter, FI; Grawunder, U; Beerli, RR

Beerli, RR (reprint author), NBE Therapeut AG, Hochbergerstr 60C, CH-4057 Basel, Switzerland.

MOLECULAR CANCER THERAPEUTICS, 2017; 16 (5): 879

Abstract

Antibody-drug conjugates (ADC) are highly potent and specific antitumor drugs, combining the specific targeting of mAbs with the potency of small-mole......

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