The ROR1 antibody-drug conjugate huXBR1-402-G5-PNU effectively targets ROR1(+) leukemia

Hu, EY; Do, P; Goswami, S; Nunes, J; Chiang, CL; Elgamal, S; Ventura, AM; Cheney, C; Zapolnik, K; Williams, E; Mani, R; Frissora, F; Mo, XK; Waldmeier, L; Beerli, RR; Peng, HY; Rader, C; Long, MX; Grawunder, U; Byrd, JC; Muthusamy, N

Muthusamy, N (corresponding author), Ohio State Univ, Div Hematol, Dept Internal Med, Columbus, OH 43210 USA.; Muthusamy, N (corresponding author), Ohio State Univ, Comprehens Canc Ctr, Columbus, OH 43210 USA.

BLOOD ADVANCES, 2021; 5 (16): 3152

Abstract

Antibody-drug conjugates directed against tumor-specific targets have allowed targeted delivery of highly potent chemotherapy to malignant cells while......

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