Discovery and structure-activity relationship studies of novel Bcl-2/Mcl-1 dual inhibitors with indole scaffold

Zhang, ZW; Hou, LH; Bai, LJ; Pei, JY; Zhao, S; Liu, D; Luan, SL; Huang, M; Zhao, LX

Huang, M; Zhao, LX (通讯作者)，Shenyang Pharmaceut Univ, Key Lab Struct Based Drugs Design & Discovery Mini, Shenyang 110016, Peoples R China.

BIOORGANIC CHEMISTRY, 2022; 125 ():

Abstract

The Bcl-2 anti-apoptotic proteins were widely overexpressed in diverse tumor cells, especially for Bcl-2 and Mcl1, which regarding as important target......

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