Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

Chitu, V; Biundo, F; Shlager, GGL; Park, ES; Wang, P; Gulinello, ME; Gokhan, S; Ketchum, HC; Saha, K; DeTure, MA; Dickson, DW; Wszolek, ZK; Zheng, DY; Croxford, AL; Becher, B; Sun, DQ; Mehler, MF; Stanley, ER

Stanley, ER (corresponding author), Albert Einstein Coll Med, Dept Dev & Mol Biol, Bronx, NY 10461 USA.

CELL REPORTS, 2020; 30 (9): 3004

Abstract

CSF-1R haploinsufficiency causes adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). Previous studies in the Csf1r(+/-) m......

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