TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

Xie, D; Stutz, B; Li, F; Chen, F; Lv, HN; Sestan-Pesa, M; Catarino, J; Gu, JL; Zhao, HY; Stoddard, CE; Carmichael, GG; Shanabrough, M; Taylor, HS; Liu, ZW; Gao, XB; Horvath, TL; Huang, YQ

Huang, YQ (通讯作者)，Yale Univ, Sch Med, Dept Obstet Gynecol & Reprod Sci, 310 Cedar St,LSOG 205C, New Haven, CT 06510 USA.;Horvath, TL (通讯作者)，Dept Comparat Med, 310 Cedar St,POB 208016, New Haven, CT 06520 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2022; 132 (19):

Abstract

The TET family of dioxygenases promote DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Hypothalamic agouti-related ......

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