Cystathionine beta-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs(-/-) mice and thrombosis-prone CBS-/- humans

Sikora, M; Lewandowska, I; Marczak, L; Bretes, E; Jakubowski, H

Jakubowski, H (corresponding author), Univ Life Sci, Dept Biochem & Biotechnol, PL-60632 Poznan, Poland.; Jakubowski, H (corresponding author), Rutgers New Jersey Med Sch, Int Ctr Publ Hlth, Dept Biochem Microbiol & Mol Genet, 225 Warren St, Newark, NJ 07103 USA.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Cystathionine beta-synthase (CBS)-deficient patients are prone to vascular thrombosis. In contrast, Cbs(-/-) mice show no abnormalities in blood coagu......

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