Alternagin-C (ALT-C), a disintegrin-like protein, attenuates alpha2beta1 integrin and VEGF receptor 2 signaling resulting in angiogenesis inhibition

dos Santos, PK; Altei, WF; Danilucci, TM; Lino, RLB; Pachane, BC; Nunes, ACC; Selistre-de-Araujo, HS

dos Santos, PK (corresponding author), Univ Fed Sao Carlos, Dept Physiol Sci, Biochem & Mol Biol Lab, Rod Washington Luis,Km 235,SP-310, BR-13565905 Sao Carlos, SP, Brazil.

BIOCHIMIE, 2020; 174 (): 144

Abstract

Angiogenesis, a crucial process in tumor progression, is mainly regulated by vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. Studi......

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