TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41

Carey, KL; Paulus, GLC; Wang, LF; Balce, DR; Luo, JW; Bergman, P; Ferder, IC; Kong, LJ; Renaud, N; Singh, S; Kost-Alimova, M; Nyfeler, B; Lassen, KG; Virgin, HW; Xavier, RJ

Xavier, RJ (corresponding author), Broad Inst MIT & Harvard, Immunol Program, Cambridge, MA 02142 USA.; Xavier, RJ (corresponding author), Broad Inst MIT & Harvard, Infect Dis & Microbiome Program, Cambridge, MA 02142 USA.; Xavier, RJ (corresponding author), Harvard Med Sch, Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA.; Xavier, RJ (corresponding author), Harvard Med Sch, Massachusetts Gen Hosp, Ctr Computat & Integrat Biol, Boston, MA 02114 USA.

CELL REPORTS, 2020; 33 (6):

Abstract

Transcription factor EB (TFEB) activates lysosomal biogenesis genes in response to environmental cues. Given implications of impaired TFEB signaling a......

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