Expansion of Tumor-Infiltrating CD8(+) T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy

Fernandez-Poma, SM; Salas-Benito, D; Lozano, T; Casares, N; Riezu-Boj, JI; Mancheno, U; Elizalde, E; Alignani, D; Zubeldia, N; Otano, I; Conde, E; Sarobe, P; Lasarte, JJ; Hervas-Stubbs, S

Hervas-Stubbs, S (reprint author), Univ Navarra, Ctr Appl Med Res CIMA, Ave Pio 12 55, Navarra 31008, Spain.

CANCER RESEARCH, 2017; 77 (13): 3672

Abstract

Recent studies have found that tumor-infiltrating lymphocytes (TIL) expressing PD-1 can recognize autologous tumor cells, suggesting that cells derive......

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