Synthesis and Reactions of 3,3-Difluoro-2-exo-methylidene Indolines

Zeidan, N; Zambri, M; Unger, S; Dank, C; Torelli, A; Mirabi, B; Lautens, M

Lautens, M (corresponding author), Univ Toronto, Dept Chem, Davenport Res Labs, Toronto, ON M5S 3H6, Canada.

ORGANIC LETTERS, 2020; 22 (9): 3688

Abstract

A dearomative electrophilic fluorination of 2-methylindoles is reported, delivering 3,3-difluoroindolines bearing an exomethylidene. The model substra......

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