Identification of osimertinib-resistant EGFR L792 mutations by cfDNA sequencing: oncogenic activity assessment and prevalence in large cfDNA cohort

Fairclough, SR; Kiedrowski, LA; Lin, JJ; Zelichov, O; Tarcic, G; Stinchcombe, TE; Odegaard, JI; Lanman, RB; Shaw, AT; Nagy, RJ

Fairclough, SR (reprint author), Guardant Hlth Inc, 505 Penobscot Dr, Redwood City, CA 94063 USA.

EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2019; 8 (1):

Abstract

Cell-free DNA (cfDNA) next-generation sequencing has the potential to capture tumor heterogeneity and genomic evolution under treatment pressure in a ......

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