The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas

Sánchez-Tilló, E; Pedrosa, L; Vila, I; Chen, YX; Györffy, B; Sánchez-Moral, L; Siles, L; Lozano, JJ; Esteve-Codina, A; Darling, DS; Cuatrecasas, M; Castells, A; Maurel, J; Postigo, A

Sánchez-Tilló, E; Postigo, A (通讯作者),Rossello 149-153, Barcelona 08036, Spain.

JCI INSIGHT, 2023; 8 (20):

Abstract

Despite being in the same pathway, mutations of KRAS and BRAF in colorectal carcinomas (CRCs) determine distinct progression courses. ZEB1 induces an ......

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