An insight into the inhibitory selectivity of 4-(Pyrazol-4-yl)-pyrimidines to CDK4 over CDK2

Dong, KK; Yang, XY; Zhao, TT; Zhu, XL

Zhu, XL (reprint author), Nanjing Tech Univ, Coll Chem Engn, State Key Lab Mat Oriented Chem Engn, \, Nanjing, Peoples R China.

MOLECULAR SIMULATION, 2017; 43 (8): 599

Abstract

Revealing selectivity mechanism of cyclin-dependent kinases (CDK) and their inhibitors is an important issue to develop potential anticancer drugs. Th......

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