Identification of ortho-Substituted Benzoic Acid/Ester Derivatives via the Gas-Phase Neighboring Group Participation Effect in (+)-ESI High Resolution Mass Spectrometry

Blincoe, WD; Rodriguez-Granillo, A; Sauri, J; Pierson, NA; Joyce, LA; Mangion, I; Sheng, HM

Sheng, HM (reprint author), Merck & Co Inc, Analyt Res & Dev, Rahway, NJ 07065 USA.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2018; 29 (4): 694

Abstract

Benzoic acid/ester/amide derivatives are common moieties in pharmaceutical compounds and present a challenge in positional isomer identification by tr......

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