The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma

Boone, MA; Taslim, C; Crow, JC; Selich-Anderson, J; Byrum, AK; Showpnil, IA; Sunkel, BD; Wang, M; Stanton, BZ; Theisen, ER; Lessnick, SL

Lessnick, SL (corresponding author), Ohio State Univ, Biomed Sci Grad Program, Columbus, OH 43210 USA.; Lessnick, SL (corresponding author), Nationwide Childrens Hosp, Abigail Wexner Res Inst, Ctr Childhood Canc & Blood Dis, Columbus, OH 43210 USA.; Lessnick, SL (corresponding author), Ohio State Univ, Mol Cellular & Dev Biol Grad Program, Columbus, OH 43210 USA.; Lessnick, SL (corresponding author), Ohio State Univ, Dept Pediat, Columbus, OH 43210 USA.

ONCOGENE, 2021; 40 (29): 4759

Abstract

Ewing sarcoma is an aggressive bone cancer of children and young adults defined by the presence of a chromosomal translocation: t(11;22)(q24;q12). The......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索