A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma

Gopal, YNV; Gammon, S; Prasad, R; Knighton, B; Pisaneschi, F; Roszik, J; Feng, NP; Johnson, S; Pramanik, S; Sudderth, J; Sui, DW; Hudgens, C; Fischer, GM; Deng, WL; Reuben, A; Peng, WY; Wang, J; McQuade, JL; Tetzlaff, MT; Di Francesco, ME; Marszalek,

Gopal, YNV (reprint author), Univ Texas MD Anderson Canc Ctr, 1515 Holcombe Blvd,Unit 2506, Houston, TX 77030 USA.

CLINICAL CANCER RESEARCH, 2019; 25 (21): 6429

Abstract

Purpose: The purpose of this study is to determine if inhibition of mitochondrial oxidative phosphorylation (OxPhos) is an effective strategy against ......

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