Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription

Stanley, SY; Borges, AL; Chen, KH; Swaney, DL; Krogan, NJ; Bondy-Denomy, J; Davidson, AR

Davidson, AR (reprint author), Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada.; Davidson, AR (reprint author), Univ Toronto, Dept Biochem, Toronto, ON M5S 1A8, Canada.

CELL, 2019; 178 (6): 1452

Abstract

Phages express anti-CRISPR (Acr) proteins to inhibit CRISPR-Cas systems that would otherwise destroy their genomes. Most acr genes are located adjacen......

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