TT-1, an analog of melittin, triggers apoptosis in human thyroid cancer TT cells via regulating caspase, Bcl-2 and Bax

Wan, LL; Zhang, DQ; Zhang, JN; Ren, LQ

Ren, LQ (reprint author), Jilin Univ, Dept Pharmacol & Toxicol, Sch Pharmaceut Sci, 1266 Fujin Rd, Changchun 130021, Jilin, Peoples R China.; Zhang, DQ (reprint author), Jilin Univ, Dept Thyroid Surg, Jilin Prov Key Lab Surg Translat Med, China Japan Unio

ONCOLOGY LETTERS, 2018; 15 (1): 1271

Abstract

Melittin is a 26 amino acid residue antimicrobial peptide with known antitumor activity. In the present study, a novel peptide TT-1, derived from meli......

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