Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics

Afosah, DK; Al-Horani, RA; Sankaranarayanan, NV; Desai, UR

Desai, UR (reprint author), Virginia Commonwealth Univ, Dept Med Chem, Richmond, VA 23219 USA.

JOURNAL OF MEDICINAL CHEMISTRY, 2017; 60 (2): 641

Abstract

Although plasmin inhibitors could be used in multiple disorders, their use has been restricted to preventing blood loss in hemostatic dysregulation be......

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