Entinostat induces antitumor immune responses through immune editing of tumor neoantigens

Truong, AS; Zhou, M; Krishnan, B; Utsumi, T; Manocha, U; Stewart, KG; Beck, W; Rose, TL; Milowsky, MI; He, XP; Smith, CC; Bixby, LM; Perou, CM; Wobker, SE; Bailey, ST; Vincent, BG; Kim, WY

Vincent, BG; Kim, WY (corresponding author), Univ North Carolina Chapel Hill UNC, Lineberger Comprehens Canc Ctr, CB 7295, Chapel Hill, NC 27599 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2021; 131 (16):

Abstract

Although immune-checkpoint inhibitors (ICIs) have been a remarkable advancement in bladder cancer treatment, the response rate to single-agent ICIs re......

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